Insulin Potentiation Therapy

An alternative to cancer therapy, Insulin Potentiation Therapy administers insulin along with lower doses of chemotherapy drugs. The theory behind IPT is that the insulin potentiates the effect of chemotherapy and other medications, and lower chemotherapy doses are needed as more of the drugs enter the cells due to insulin.

Developed by Dr. Donato Perez Garcia in Mexico in the 1930s, Insulin Potentiation Therapy has been used along with other unconventional therapies for several years. IPT advocates believe cancer cells to consume more sugar than healthy cells and therefore are more sensitive to insulin.

If cancer cells can be activated through external insulin, a reduced dose of chemotherapy drugs (just one-tenth of the normal dose) can provide the same effects with fewer adverse reactions as the normal dose. IPT proponents believe that the permeability of cell membranes is increased by insulin which leads to increase of cytotoxic effects of cancer drugs and increased intracellular concentrations.

Although advocates cite various anecdotal cases suggesting the effectiveness of IPT, no data comparing the effectiveness of IPT to conventional chemotherapy is available. No clinical trials have been performed to validate IPT claims and is it unclear if insulin also increases the toxic effects of chemotherapy on healthy cells.

Side effects of IPT can include hypoglycemic reactions and should not be performed if you are taking hypoglycemic agents. As a rule of thumb, as insulin can cause blood sugar to decrease to dangerously low levels and causing symptoms like headache and delirium, insulin should not be taken by nondiabetics.

Before undergoing IPT therapy, it is important to note that IPT therapy is an alternative treatment to traditional chemotherapy, and while most medications used in this therapy such as insulin and chemotherapy drugs are FDA approved, they are administered “off-label” by IPT clinics.

Learn more about IPT Cancer Therapy

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