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What Is IPT Therapy

What Is IPT Therapy

Also known as low-dose chemotherapy, IPT is an alternative cancer treatment that is gaining more attention from the medical industry as reports of its effectiveness continue. At its simplest, IPT uses insulin to elevate the effectiveness of chemotherapy while lessening its negative effects. Insulin potentiation effects are two-fold.

There are only a handful of wellness centers across America which offers this service. My Gentle Wellness Center in Fairfax, VA is one of them! Please contact us to set up an appointment for effective alternative cancer treatment!

Glucose Infusion

Cancer cells are armed with six to 15 times more insulin receptors than normal cells. Though this allows them to compete better for food, it also makes them vulnerable. As they greedily open their membranes in response to insulin levels, chemotherapy is administered, followed by a large dose of glucose. The cancerous cells more easily absorb the chemo in an attempt to devour the glucose. Less doses of chemo are needed, therefore side effects are limited.

Healthy Cell Protection

Because healthy, normal cells have far fewer insulin receptors, they remain safeguarded against the influx of both glucose and chemotherapy, allowing more of the drug to fight the cancer as they were intended. With less damage to the immune system, patients are able to stabilize their metabolism, continue healthy eating patterns and avoid the “wasting stage” so often seen in cancer patients.

Treating a variety of cancers, our physicians are among just 135 in the world who are trained in IPT treatments. As integrative health practitioners, we believe in treating the body/mind/spirit holistically. We thoroughly test each patient in order to determine if IPT is appropriate for them and to develop a comprehensive care plan for each.

If you would like to learn more about IPT or other innovative, natural healing treatments, contact our Fairfax wellness center now.

IPT Cancer Treatment

Insulin potentiation therapy (IPT) is an alternative to conventional chemotherapy for the treatment of most cancers. There is growing interest and consumer demand for alternatives to conventional cancer therapies, driven largely by fear of the toxicities and side effects of conventional chemotherapy drugs, and the manner in which they are administered. With IPT, the same chemotherapeutics are used that would be used conventionally; however insulin administered just prior to chemotherapy is coupled with a significantly lower dose of the chemotherapy drug. The feared side effects are many orders of magnitude lower; most patients can continue to go about their daily lives.

Dr. Joseph Shaw Jones, Medical Director at Gentle Wellness Center in Fairfax, Virginia, is one of over a hundred physicians worldwide using some form of insulin potentiation therapy, and the only one in the mid-Atlantic area certified in IPTLD, under the originator of insulin potentiation, Dr. Donato Garcia.

How Does Insulin Potentiation Therapy Work?

Normal cells and cancer cells need glucose for energy. This glucose enters cells via a large protein that bridges the cell membrane called the insulin receptor. In addition to allowing glucose to enter cells, insulin also increases cell membrane permeability to other substances, including chemotherapy drugs. Additionally, it has been discovered that cancer cells have a greater concentration of these insulin receptors present, on the order of 10,000 to 1 vs. normal cells. A Georgetown University Medical School study in the 1990s showed the chemotherapy drug methotrexate had the ability to enter cancer cells at a rate 10,000 times greater when the cells were prepared with insulin.

Consequently, insulin ‘potentiates’ by allowing comparatively higher concentrations of chemotherapy drugs to enter the cancer cells vs. normal cells.

Only a select few locations across America offer these services. Fortunately, My Gentle Wellness Center in Fairfax, VA is one of those locations! Contact us today to set up an appointment for effective alternative cancer treatment!

IPT Works in Combination with Low-Dose Chemotherapy

Our cells, normal and cancerous, have a life cycle comprised of phases, or periods of active growth, DNA synthesis and dormancy. Some chemotherapeutics are effective throughout the cell cycle, and some are effective only during periods of cell growth and synthesis. Insulin has been found to synchronize cancer cells in the phase where they are most susceptible to chemotherapy drugs. This phenomenon, along with increased cell membrane permeability, may explain the observed effectiveness of chemotherapy protocols where doses of the drugs are 10-20% per week of conventional doses when insulin is given prior to chemotherapy.


It has been known for some time that administration of lower doses of chemotherapeutics, given more often (weekly or bi-weekly, are tolerated far better than a single high dose given every 3 or 4 weeks, and in most cases are not inferior to the high dose protocols, and in many circumstances, superior. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156829/



What Does the Research Say About Low-Dose Chemotherapy for Cancer?

Early work by IPT pioneers such as Steven Ayre, MD, and Donato Garcia, MD brought IPT to the forefront of alternative cancer therapy. There have been favorable small comparative studies published regarding IPT:



And a number of favorable anecdotal case reports:

https://www.ncbi.nlm.nih.gov/pubmed/20148468, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567024/#b102 are examples.

Presentations given at national and international IPT conferences reveal robust but unpublished support.

In practice across the US, IPT is administered with significant differences in drug dosing and target blood sugar. Here, the recommendations of Donato Garcia, MD, developer of IPTLD, are adhered to regarding the ‘therapeutic moment’. Drugs used in protocol recommendations are derived from the National Comprehensive Cancer Network, your oncologist’s recommendations and your personal history; the average patient receives, cumulatively, over the course of treatment, approximately 70-80% of the dose recommended conventionally, given on a weekly basis.

Currently, IPT is an alternative to conventional cancer therapy, and is not considered the standard of care for cancer treatment. All patients must have a tissue diagnosis, and all must have seen, or be willing to accept referral to, a board certified oncologist to be able to make an informed decision regarding their treatment options.